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KMID : 0360919680110090760
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Journal of the Korean Medical Association
1968 Volume.11 No. 9 p.760 ~ p.764
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RESPIRATORY GAS TENSIONS OF HUMAN AND DOG CYSTIC BILE
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呂雄潤/Ryo, Ung Yun
金根周/鄭雲杓/郭然植/Kim, Kun Joo/Chung, Woon Pyo/Kwak, Yun Sick
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Abstract
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The respiratory gas tensions and pH of bladder bile have been measured and the significance of obtained results was discussed in present study.
Bladder bile was sampled in seven patients receiabdominal surgery for diagnostic laparotomy or simple appendectomy and in fifteen experimental dogs. Air tight and sterile syringe and needles were used for the sampling.
The content of O₂and CO₂in the bile was analysed by Van Slyke manometric apparatus, pH was measured by means of Beckman Expandomatic pH meter. Partial pressure of the gases was calculated dividing volume by solubility coefficient of the gas to the plasma.
The content and partial pressure of O₂in average of human bladder bile were 1.38 volume %, and 58.7 mmHg., and those of CO₂were 42.6 volume %,and 81.9 mmHg., respectively. The averaged value of human bladder bile pH was 7.13.
Comparatively higher content of CO₂in bladder bile than surrounding tissue was attributed to the bicarbonate in the bile. Lower value of measured human bladder bile pH than expected was seemed to be due to pre-operative fasting of patients.
In dog bladder bile, volume of O₂, pO₂, volume of CO₂, pCO₂, and pH averaged 0.39 volume %, 16.6 mmHg, 18.3 volume %, 35.2 mmHg, and 6.66 respectively.
All the data measured in dog bladder bile were significantly lower than those of human bladder bile. Such low respiratory gas tensions in dog bladder bile were seemed attributed to that animals had been suffered from hypoxic-hyperventilation during the course of experiment. Low oxygen hyperventilation can reduce both of O₂and CO₂ from the tissuse. The exchange rate and tensions of the respiratory gases in dog bile will be further elucidated.
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